MRX Antithrombin Ref. No. K5033
MRX Antithrombin (AT) is a liquid, functional, chromogenic assay measuring the AT activity based on the inhibition of FXa in the presence of heparin.
Description
The chromogenic AT assay measures the AT activity (functional AT) by a two-stage method as follows: An excess of FXa is added to the citrated plasma sample pre-diluted with saline and in the presence of heparin. The residual FXa cleaves the peptide linked to the chromogenic FXa substrate, which results in the release of free p-nitroaniline (pNA). The amount of released pNA is measured at 405 nm and the absorbance is inversely proportional to the AT activity in the patient plasma, expressed as IU/mL or %.
Additional information
| Size | 4×6 mL FXa, 2×3 mL Substrate |
|---|---|
| Storage Requirements | 2-8 °C |
